Table 1. Drive characteristics.

zpg promoter Shared characteristics: Female HDR cut rate = 0.99 Male HDR cut rate = 0.96 Female germline resistance rate = 0.01 Male germline resistance rate = 0.02 Maternal embryo resistance rate = 0.08	nos promoter Shared characteristics: Female HDR cut rate = 0.99 Male HDR cut rate = 0.98 Female germline resistance rate = 0.01 Male germline resistance rate = 0.01 Maternal embryo resistance rate = 0.14
zpg drive Paternal Cas9 deposition rate = 0.69 Female somatic fitness cost = 0.3	nos drive Female somatic fitness cost = 0.45 Male somatic fitness cost = 0.45
zpg2 drive Female somatic fitness cost = 0.5	nosF drive Female somatic fitness cost = 0.45
zpgX drive Paternal Cas9 deposition rate = 0.69 Female somatic fitness cost = 0.3 X-shredding rate = 0.93	nosF2 drive Female somatic fitness cost = 0.15
zpg2X drive Female somatic fitness cost = 0.5 X-shredding rate = 0.93	nosF3 drive No somatic fitness costs.