Gene expression profile of neuroinflammatory markers in all studied groups: (a) TNF-α expression in the brain of young rats, (b) TNF-α expression in the brain of aged rats, (c) IL-6 expression in the brain of young rats, (d) IL-6 expression in the brain of aged rats, (e) IL-1β expression in the brain of young rats, (f) IL-1β expression in the brain of aged rats, (g) IDO-1 expression in the brain of young rats, (h) IDO-1 expression in the brain of aged rats, (i) MCP-1 expression in the brain of young rats, and (j) MCP-1 expression in the brain of aged rats. Values are expressed as the mean ± SEM (n = 3). Means of the same measured parameter with different letters in each bar (A–D) are significantly different (p < 0.01); the largest data value takes the letter (A), and the smallest data value takes the letter (D).