Fig. 8. Inhalation exposure to cigarette smoke or acrolein alters supraventricular conduction and ventricular repolarization.
Bars represent least square means (±SEM) of change from 5-min baseline in P duration, PR interval, J amplitude, QTc interval, and uncorrected QT (gray circles) according to exposure phases (a–l). Blue dashes mark Air mean (n = 8) and dot-dashes mark VG mean as reference. Significance determined by two-sided P < 0.05 (vs. Air: star or, for QT, gray asterisk) in mixed model analyses. For Acrolein and MCS 1R5F, n = 8, and for MCS 3R4F, n = 6. Black asterisk indicates nicotine present. For averages of individual subjects by phase, and simple means and standard errors, see Supplementary Fig. 10. Source data, including all p values, are provided as a Source Data file.