Table 1.
Estimated association of changes in ECG repolarization parameters with VPB incidence upon inhalation exposure to nicotine-free and nicotine-containing aerosols
| Effect estimate (%) | 95% CI | P-value | Interaction P-value | |
|---|---|---|---|---|
| S amplitude (change in VPB incidence per 0.01-mV decrease from baseline) | ||||
| Nicotine-free exposures | −3.1 | (−12.4, 7.1) | 0.5362 | 0.0730 |
| Nicotine aerosols | 20.2a | (4.6, 38.2) | 0.0095 | |
| J amplitude (change in VPB incidence per 0.1-mV increase from baseline) | ||||
| Nicotine-free exposures | −15 | (−48, 39) | 0.5169 | 0.0909 |
| Nicotine aerosols | 151a | (46, 329) | 0.0008 | |
aSignificant association determined by generalized estimating equation and two-sided P < 0.05.