Table 2.
Comparison of cohort characteristics
| Median (1st quartile-3rd quartile); min–max | SIBDCS | CoLaus¦PsyCoLaus | Pearson’s r (Pr)/Cramer’s V (CV) | P value | |
|---|---|---|---|---|---|
|
Neuroticism SIBDCS N = 1119 CoLaus¦PsyCoLaus N = 2535 |
19.0 (14.0–25.0); 0–46.0 | 18.0 (13.0–23.0); 0–45.0 | Pr = 0.074 | < 0.001 | |
|
Extraversion SIBDCS N = 1097 CoLaus¦PsyCoLaus N = 2535 |
27.0 (22.0–31.0); 1.0–43.0 | 28.0 (24.0–32.0); 3.0–45.0 | Pr = 0.096 | < 0.001 | |
|
Opennessa SIBDCS N = 1076 CoLaus¦PsyCoLaus N = 2471 |
23.0 (19.0–27.0); 5.0–40.0 | 21.0 (19.0–24.0); 7.0–33.0 | Pr = 0.144 | < 0.001 | |
|
Agreeableness SIBDCS N = 1083 CoLaus¦PsyCoLaus N = 2535 |
33.0 (29.0–36.0); 9.0–48.0 | 18.0 (30.0–37.0); 12.0–48.0 | Pr = 0.063 | < 0.001 | |
|
Conscientiousness SIBDCS N = 1098 CoLaus¦PsyCoLaus N = 2535 |
36.0 (32.0–40.0); 10.0–48.0 | 35.0 (32.0–39.0); 7.0–48.0 | Pr = 0.028 | 0.096 | |
|
NEO-FFI(-R) risk score SIBDCS N = 1119 CoLaus¦PsyCoLaus N = 2473 |
11.2 (8.8–13.6); 0.0–24.5 | 11.1 (9.3–12.9); 2.6–22.1 | Pr = 0.019 | 0.251 | |
|
NEO-FFI(-R) risk groups (Cut-off = 11.3)b SIBDCS N = 1119 CoLaus¦PsyCoLaus N = 2473 |
High risk | 554/1119 (49.5%) | 1148/2473 (46.4%) | CV = 0.029 | 0.093 |
|
Type D personality SIBDCS N = 1101 CoLaus¦PsyCoLaus N = 2578 |
Yes | 336/1101 (30.5%) | 397/2578 (15.4%) | CV = 0.173 | < 0.001 |
|
Sex SIBDCS N = 1119 CoLaus¦PsyCoLaus N = 2600 |
Male | 534/1119 (47.7%) | 1111/2600 (42.7%) | CV = 0.046 | 0.006 |
|
Age (years) SIBDCS: N = 1119 CoLaus¦PsyCoLaus: N = 2600 |
41.3 (31.0–52.6); 14.8–84.6 | 59.4 (41.5–67.6); 41.5–54.2 | Pr = 0.515 | < 0.001 | |
|
BMI (kg/m2) SIBDCS N = 1081 CoLaus¦PsyCoLaus N = 2544 |
23.2 (21.0–26.1); 14.7–55.1 | 25.4 (22.8–28.3); 15.8–44.8 | Pr = 0.217 | < 0.001 | |
| Smoking status SIBDCS N = 1110, CoLaus¦PsyCoLaus N = 2558 | Smoker | 312/1110 (28.1%) | 507/2558 (19.8%) | CV = 0.091 | < 0.001 |
| Daily alcohol consumption SIBDCS: N = 1103, CoLaus¦PsyCoLaus: N = 2573 | Yes | 88/1103 (8.0%) | 726/2573 (28.2%) | CV = 0.223 | < 0.001 |
|
Academic education SIBDCS N = 1091, CoLaus¦PsyCoLaus N = 2599 |
Yes | 157/1091 (14.4%) | 706/2599 (27.2%) | CV = 0.138 | < 0.001 |
Cohort characteristics of study participants from the SIBDCS at enrolment and the CoLaus¦PsyCoLaus cohort at NEO-FFI assessment. P values were calculated using the Mann–Whitney U or χ2 tests, respectively. Effect sizes were calculated as Pearson’s r or Cramer’s V, respectively. Numbers diverging from 1154 (SIBDCS) or 2600 (CoLaus¦PsyCoLaus), respectively, are due to missing data for certain variables
NEO-FFI NEO-five-factor inventory, SIBDCS swiss IBD cohort study
aNEO-FFI items 28 and 33 are missing because they were not assessed in the SIBDCS (compare limitations)
bThe cut-off value (11.3) to interpret NEO-FFI risk groups is the mean NEO-FFI risk score of all included SIBDCS patients (training and validation data)
Bold values indicate significant P-values (i.e. P < 0.05) or moderate-high correlations (i.e. Pr/CV > 0.500), respectively