Table 2.
Cerebellar gray matter changes between OCD and TSpure patients
Cerebellar volume (mL) | TSpure* (355.4 ± 11.3) |
TS + OCD (354.7 ± 11.3) |
OCD* (341.8 ± 21.2) |
Ctrls (345.7 ± 19.4) |
F/p value 2.4/0.08 *OCD < TSpure |
|
---|---|---|---|---|---|---|
R_Crus I | 37.51 ± 1.2 | 37.5 ± 1.8 | 35.9 ± 2.5 | 36.9 ± 2.1 | 2.9/0.04* | |
L_Crus I | 37.9 ± 1.6 | 37.7 ± 2.1 | 36.1 ± 2.5 | 37.2 ± 1.6 | 3.1/0.03* | |
R_lobule VIIIb | 12.0 ± 0.6 | 11.5 ± 0.7 | 11.1 ± 0.7 | 11.4 ± 0.8 | 3.3/0.04* | |
L_lobule VIIIb | 12.5 ± 0.5 | 12.4 ± 0.9 | 11.7 ± 0.6 | 12.0 ± 0.9 | 2.7/0.02* |
The above table depicts significant cerebellar gray matter (GM) differences in bilateral crus I and bilateral VIIIb lobule between obsessive–compulsive disorder (OCD) and TS patients without comorbidity (TSpure)
*Denotes significant group differences obtained via multivariate analysis of covariance (MANCOVA) followed by post hoc two-sample t-test. Results are Bonferroni corrected (p < 0.05) for multiple comparisons