Table 4.
Descriptive statistics of 17 candidate circadian genes’ expression levels in placenta from PE without PTB (Term-PE) vs. non-PE without PTB (Term) in GSE75010-157 dataset.
| Gene | Term | Term-PE | pb | FDRc | ||
|---|---|---|---|---|---|---|
| n | Meana (SD) | n | Mean (SD) | |||
| ARNTL | 42 | 7.22 (0.33) | 31 | 7.39 (0.41) | 0.0619 | 0.1754 |
| ARNTL2 | 42 | 8.03 (0.37) | 31 | 7.96 (0.39) | 0.3919 | 0.5626 |
| CLOCK | 42 | 9.06 (0.33) | 31 | 8.73 (0.69) | 0.0168 | 0.0952 |
| CRY1 | 42 | 8.55 (0.34) | 31 | 8.52 (0.51) | 0.7561 | 0.8034 |
| CRY2 | 42 | 8.44 (0.24) | 31 | 8.34 (0.30) | 0.0943 | 0.2004 |
| NPAS1 | 42 | 6.57 (0.37) | 31 | 6.77 (0.46) | 0.0449 | 0.1527 |
| NPAS2 | 42 | 9.07 (0.29) | 31 | 8.93 (0.34) | 0.0724 | 0.1758 |
| NPAS3 | 42 | 6.58 (0.44) | 31 | 6.49 (0.41) | 0.3971 | 0.5626 |
| NR1D1 | 42 | 7.33 (0.34) | 31 | 7.36 (0.33) | 0.6501 | 0.7368 |
| NR1D2 | 42 | 8.92 (0.40) | 31 | 8.61 (0.56) | 0.0120 | 0.0952 |
| PER1 | 42 | 7.35 (0.26) | 31 | 7.31 (0.38) | 0.6164 | 0.7368 |
| PER2 | 42 | 8.05 (0.32) | 31 | 7.99 (0.29) | 0.3812 | 0.5626 |
| PER3 | 42 | 7.34 (0.30) | 31 | 7.16 (0.30) | 0.0137 | 0.0952 |
| RORA | 42 | 8.77 (0.32) | 31 | 8.58 (0.41) | 0.0308 | 0.1309 |
| RORB | 42 | 6.55 (0.58) | 31 | 6.84 (0.97) | 0.1535 | 0.2899 |
| RORC | 42 | 6.61 (0.35) | 31 | 6.59 (0.36) | 0.8158 | 0.8158 |
| TIMELESS | 42 | 7.78 (0.35) | 31 | 7.72 (0.40) | 0.5378 | 0.7033 |
aMean of gene expression values, normalized and log2-transformed.
Bold values denote statistical significance (p < 0.05 and FDR < 0.10).