Table 1.
Characteristics | |
---|---|
Age, years (median [IQR]) (range) | 37.5 [29–50] (18–83) |
Sex, male [n (%)] | 337 (61.1) |
BMI (kg/m2), (median [IQR]) (range)∗ | 24 [22–27] (15–49) |
History of alcohol abuse [n (%)]† | 30 (5.4) |
History of intravenous drug use [n (%)]‡ | 10 (2.3) |
Country of birth [n (%)]§ | |
France | 120 (22.1) |
Europe, excluding France | 59 (10.9) |
North Africa | 38 (7.0) |
Middle East | 24 (4.4) |
Asia | 56 (10.3) |
West Indies | 34 (6.3) |
Pacific | 1 (0.2) |
Sub-Saharan Africa | 210 (38.7) |
Coinfections [n (%)] | |
HIV¶ | 13 (2.4) |
HCV∗∗ | 22 (4.0) |
HDV | 33 (6.0) |
HBeAg-negative [n (%)] | 496 (90.0) |
Detectable HBV DNA [n (%)] | 520 (94.2) |
HBV DNA level (log IU/ml), (median [IQR]) (range) | 3.3 [2.4–4.4] (1.0–9.1) |
HBV DNA >2,000 IU/ml [n (%)] | 251 (48.5) |
HBsAg level (log IU/ml), median [IQR]) (range) | 3.6 [3.0–4.1] (-0.8 to 5.4) |
HBV genotype [n (%)]†† | |
A | 109 (25.7) |
B | 22 (5.2) |
C | 27 (6.4) |
D | 147 (34.7) |
E | 116 (27.4) |
F | 1 (0.25) |
G | 2 (0.50) |
Fibrosis stage distribution [n (%)]‡‡ | |
F0–F1 | 296 (71.0) |
F2 | 56 (13.4) |
F3 | 26 (6.2) |
F4 | 39 (9.4) |
ALT level (U/L) (median [IQR]) (range)§§ | 33 [22–52] (5–4,043) |
ALT >40 U/L [n (%)] | 194 (37.8) |
Treatment eligibility [n (%)]¶¶ | 151 (29.1) |
BMI is missing in 159 patients.
History of alcohol abuse is missing in 71 patients.
History of intravenous drug use is missing in 109 patients.
Country of birth is missing in 10 patients.
HIV status is missing in 20 patients.
HCV status is missing in 7 patients.
HBV genotype was not determined in 129 patients owing to HBV DNA level <2.5 log IU/ml or undetectable HBV DNA.
Fibrosis stage is missing in 135 patients.
ALT level is missing in 39 patients.
According to the 2017 EASL Clinical Practice Guidelines,10 only HBV-monoinfected patients were considered. Inconclusive findings in 23 patients.