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. 2022 Oct 12;13:1023867. doi: 10.3389/fendo.2022.1023867

Table 2.

Baseline characteristics by triglyceride–glucose (TyG) quartiles in the high-stroke-risk population.

Total Q1 Q2 Q3 Q4 p-value
TyG ≤8.570243 8.570243–8.946032 8.946032–9.369544 ≥9.369544
N 1,038 260 260 259 259
Region 0.64
 Urban, n (%) 656 (63.20) 164 (63.08) 160 (61.54) 172 (66.41) 160 (61.78)
 Rural, n (%) 382 (36.80) 96 (36.92) 100 (38.46) 87 (33.59) 99 (38.22)
Age (years) 58.66 ± 9.77 59.11 ± 9.27 58.32 ± 10.30 58.61 ± 10.03 58.63 ± 9.50 0.83
Gender, male, n (%) 350 (33.72) 76 (29.23) 77 (29.62) 88 (33.98) 109 (42.08) 0.006**
Eating habits 0.72
 High-salt diet 147 (14.16) 35 (13.46) 43 (16.54) 36 (13.90) 33 (12.74)
 Oil-heavy diet 311 (29.96) 76 (29.23) 84 (32.31) 73 (28.19) 78(30.12)
 Sweet tooth 580 (55.88) 149 (57.31) 133 (51.15) 150 (57.92) 148 (57.14)
Meats and vegetables 0.36
 Balanced 89 (8.57) 20 (7.69) 27 (10.38) 18 (6.95) 24 (9.27)
 Carnivorous diet 240 (23.12) 54 (20.77) 65 (25.00) 54 (20.85) 67 (25.88)
 Plant-based diet 709 (68.30) 186 (71.54) 168 (64.62) 187 (72.20) 168 (64.86)
Daily vegetable intake, n (%) 543 (52.31) 136 (52.31) 135 (51.92) 135 (52.12) 137 (52.90) 0.99
Daily fruit intake, n (%) 347 (33.43) 87 (33.46) 93 (35.77) 81 (31.27) 86 (33.20) 0.78
Alcohol consumption, n (%) 0.88
 Never 837 (80.64) 217 (83.46) 210 (80.77) 207 (7.92) 203 (78.38)
 Heavy drinking 164 (15.80) 35 (13.46) 40 (15.38) 43 (16.60) 46 (17.76)
 Light/moderate drinking 37 (3.56) 8 (3.08) 10 (3.85) 9 (3.47) 10 (3.85)
 Family history of CHD, n (%) 32 (3.08) 11 (4.23) 11 (4.23) 4 (1.54) 6 (2.32) 0.11
Family history of hypertension, n (%) 314 (30.25) 69 (26.54) 69 (26.54) 79 (30.50) 97 (37.45) 0.01*
Family history of diabetes, n (%) 151 (14.54) 25 (9.62) 32 (12.31) 44 (17.00) 50 (19.31) 0.004**
SBP (mmHg) 134.80 ± 14.06 132.48 ± 14.23 133.30 ± 12.96 136.35 ± 13.95 137.09 ± 14.59 <0.001***
DBP (mmHg) 81.79 ± 8.74 80.50 ± 8.29 80.69 ± 8.08 82.37 ± 9.32 83.63 ± 8.88 <0.001***
Height (cm) 160.54 ± 8.00 160.36 ± 0.15 160.30 ± 7.32 160.05 ± 7.80 161.46 ± 8.65 0.229
Weight (kg) 64.29 ± 10.08 60.44 ± 9.00 63.59 ± 9.62 65.44 ± 8.87 67.69 ± 11.27 <0.001***
Waist circumference (WC) (cm) 81.24 ± 9.12 77.58 ± 8.37 80.71 ± 8.25 83.02 ± 9.12 83.65 ± 9.49 <0.001***
BMI (kg/m2) 24.96 ± 3.67 23.55 ± 3.43 24.74 ± 3.26 25,61 ± 3.85 25.95 ± 3.66 <0.001***
FBG (mmol/L) 6.89 ± 1.58 6.26 ± 0.65 6.55 ± 0.89 6.92 ± 1.58 7.84 ± 2.21 <0.001***
Hemoglobin A1c (%) 6.33 ± 1.42 5.81 ± 0.98 6.06 ± 1.08 6.40 ± 1.25 7.05 ± 1.90 <0.001***
Triglyceride (TG) (mmol/L) 1.75 ± 1.09 0.97 ± 0.12 1.12 ± 0.32 1.80 ± 0.41 3.14 ± 1.22 <0.001***
Total cholesterol (TC) (mmol/L) 4.82 ± 1,21 4.54 ± 1.27 4.76 ± 1.13 4.88 ± 1.19 5.12 ± 1.20 <0.001***
HDL-C (mmol/L) 1.28 ± 0.47 1.56 ± 0.55 1.33 ± 0.48 1.18 ± 0.39 1.07 ± 0.27 <0.001***
LDL-C (mmol/L) 2.20 ± 1.08 2.05 ± 1.05 2.35 ± 1.03 2.30 ± 1.09 2.10 ± 1.11 0.002**
Homocysteine (μmol/L) 11.64 ± 8.59 12.69 ± 10.01 11.37 ± 8.33 10.63 ± 7.01 11.89 ± 8.64 0.047*
VAI 2.41 ± 2.02 0.91 ± 0.36 1.59 ± 0.57 2.42 ± 0.91 4.71 ± 2.60 <0.001***
TG/HDL-C 1.53 ± 1.27 0.56 ± 0.19 0.98 ± 0.30 1.51 ± 0.49 3.01 ± 1.60 <0.001***
TyG-BMI 224.89 ± 38.74 195.36 ± 28.55 216.75 ± 28.70 234.25 ± 35.19 253.33 ± 36.09 <0.001***
TyG-WC 731.85 ± 103.87 644.29 ± 72.61 707.42 ± 72.93 758.77 ± 83.77 817.37 ± 96.53 <0.001***
TyG-WHtR 4.57 ± 0.66 4.03 ± 0.48 4.42 ± 0.46 4.75 ± 0.57 5.07 ± 0.61 <0.001***
Increased IMT (%) 228 (21.97) 58 (22.31) 57 (21.92) 50 (19.31) 63 (24.32) 0.59
Carotid plaque (%) 385 (37.09) 80 (30.77) 92 (35.38) 100 (38.61) 113 (43.63) 0.02*
CAS (%) 64 (6.17) 12 (4.62) 12 (4.62) 18 (6.95) 22 (8.49) 0.18

LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; CHD, coronary heart disease; SBP, systolic blood pressure; DBP, diastolic blood pressure; FBG, fasting blood glucose; TyG, triglyceride–glucose; WHtR, waist-to height ratio; VAI, visceral adiposity index.

*p< 0.05; **p< 0.01; ***p< 0.001.