Figure 3.

Effects of the cholinergic neurons lesion in the DMV on gastrointestinal motility in mice. Various gastrointestinal markers were assessed in WT mice with mu p75‐SAP‐ treatment, or in A53T mice with ghrelin (G‐A53T) or scrambled ghrelin peptide (P‐A53T). A,G) Stool wet weight. B,H) Stool dry weight. C,I) stool frequency. D,J) Stool water contents. E) Small intestinal motility. F) Gastric emptying rate. A–F) All data were mean ± SEM (t‐test, *P < 0.05, compared with the control), n ≥ 5 for each group. G–J) All data were mean ± SEM (t‐test, *P < 0.05, **P < 0.01, ***P < 0.001, G‐A53T vs P‐A53T at the same time point), n = 5 for each group.