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. 2022 Oct 12;12:999654. doi: 10.3389/fonc.2022.999654

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Copyright © 2022 Li, Liu, Chen, Zhang, Wu and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Univariate and multivariate analyses revealed that risk score was an independent prognostic predictor in the TCGA-RNA-Seq cohort (A). Construction of decision tree based on risk score, age and stage. The younger and older subgroup were divided based on the median value of age (B). Construction of nomogram based on risk score, age and stage (C). Calibration plots of the nomogram for predicting the probability of OS at 1, 3, and 5-years in the TCGA-RNA-Seq cohort (D–F); KM survival plot analysis showed that patients with high-risk had a worse OS than patients with low-risk subgroup in both TCGA-RNA-Seq cohort and HG-U133_Plus_2 cohort (G, H).