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. 2022 Sep 6;20(8):627–643. doi: 10.18502/ijrm.v20i8.11752

Table 4.

Differentiation potential of human amniotic epithelial stem cells


Author, year (Ref) Regenerated tissue Treatment
Kajiwara et al ., 2017, Kunisaki, 2018 (67, 69) Fetal Congenital diaphragmatic hernia, abdominal wall defects, spinal bifida, and congenital heart
Cipriani et al ., 2007 (68) Peripheral and central nervous Neurodegenerative disease such as cerebral ischemia
Di Baldassarre et al ., 2018 (70) Cardiac Cardiomyoplasty
Chun et al. , 2014 (71) Skeletal muscle Duchenne muscular dystrophy
Carraro et al ., 2008 (72) Lung Lung-related disorders such as COVID-19
Morigi et al ., 2014 (73) Kidney Acute ischemia-reperfusion and acute tubular necrosis
Wang et al ., 2018 (74) Hepatic Liver fibrosis
Maraldi et al ., 2013 (75) Bone and cartilage Extensive bone defects disease
Chang et al ., 2018 (76) Ovarian Ovarian dystrophy and fertility
Gosemann et al ., 2012 (77) Inflammatory and autoimmune diseases Graft-vs.-host disease, inflammatory bowel disease, experimental autoimmune encephalomyelitis, and systemic lupus erythematosus