Knockout of Col12a1 mRNA expression in tendon targeted conditional mice. Quantitative real-time PCR analyses of Col12a1 mRNA expression in Col12a1Δten/Δten FDLs is reduced to baseline while expression in the Col12a1+/Δten FDLs was ∼ 25% of control values. Day 10 Control (n = 8, including WT n = 4, Scx-Cre n = 2, Col12a1+/flox n = 2), Col12a1+/Δten (n = 3), Col12a1Δten/Δten (n = 3), and Col12a1-/- (n = 1) mice (*p < 0.05).