Fig. 3.

The effect of dietary ellagic acid (EA) supplementation and fecal microbiota transplantation (FMT) on the gene expression of inflammatory cytokines and antioxidant factors in weanling piglets. The genes of antioxidant indices in jejunum tissues including the following: (A) HO-1, (B) NQO-1, (C) GCLC, and (D) GCLM. The genes of inflammatory cytokines in jejunum tissues including the following: (E) TNF-α, (F) IL-6, (G) IL-1α, (H) IL-1β, and (I) IL-10. Ctrl, the control group, where piglets were fed the basal diet; EA, the EA group, where piglets were fed the basal diet supplemented with EA; FEA, the FEA group, where piglets were fed the basal diet and received FMT from EA-treated piglets. HO-1 = heme oxygenase −1; NQO-1 = quinone oxidoreductase-1; GCLC = glutamate cysteine ligase catalytic subunit; GCLM = glutamate cysteine ligase regulatory subunit; TNF-α = tumor necrosis factor–α; IL-6 = Interleukin-6; IL-1β = interleukin-1β; IL-1α = interleukin-1a; and IL-10 = interleukin-10. Data presented as mean ± SEM and significance was presented as ∗P < 0.05 and ∗∗P < 0.01 (n = 7).