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. 2022 Jun 22;28(4):827–840. doi: 10.3350/cmh.2022.0068

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Copyright © 2022 by The Korean Association for the Study of the Liver

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Transcriptome analysis of auranofin in LX-2 cells. (A) Venn diagram with contrasting regulation of TGF-β1/Cont, TGF-β1+AR50/Cont, TGF-β1+AR50/TGF-β1 from transcriptome analysis. Genes regulated by auranofin treatment were expressed as a (B) scatter plot of TGF-β1+AR50/TGF-β1. Gene correlation was performed using a (C, D) string database tool. (E, F) GSEA analysis results of transcriptomes and their (G) heatmaps. TGF, transforming growth factor; FDR, false discovery rate; NOM, normalized enrichment score.