Cytotoxic activity (IC₅₀ values) of copper(ii) complexes A–G against MRC5, LS174T, A549, and HeLa cells at 72 h of treatment^a.

Compounds	MRC5 IC50 (μM)	LS174T IC50 (μM)	A549 IC50 (μM)	HeLa IC50 (μM)
A	86.65 ± 1.40	>200	74.65 ± 8.84	182.17 ± 4.95
B	11.44 ± 1.8	19.61 ± 2.73	12.90 ± 1.24	15.24 ± 2.33
C	45.07 ± 1.79	47.00 ± 0.63	48.55 ± 2.65	46.37 ± 4.5
D	15.45 ± 2.70	35.55 ± 2.89	14.94 ± 1.96	17.86 ± 0.15
E	18.85 ± 1.11	39.95 ± 1.31	13.98 ± 3.17	26.79 ± 1.5
F	13.12 ± 2.64	22.93 ± 2.33	12.74 ± 1.82	15.41 ± 1.23
G	20.77 ± 3.5	24.98 ± 2.69	15.67 ± 0.23	36.12 ± 0.73
cisPt	9.35 ± 1.29	5.54 ± 1.03	13.21 ± 0.89	4.91 ± 0.74

^aIC₅₀ values (μM) were expressed as the mean ± SD determined from the results of the MTT assay in three independent experiments.