Table 5.
Modeling of high density lipoprotein cholesterol efflux capacity.
| Univariate | Multivariate | |||
|---|---|---|---|---|
| (R2 = 0.484) | ||||
| Estimate | p-Value | Estimate | p-Value | |
| ApoA1 | 0.0032 | <0.001 | 0.0029 | <0.001 |
| Glyc A | −0.0004 | <0.001 | −0.0014 | 0.137 |
| Age | −0.0037 | 0.180 | 0.0005 | 0.819 |
| COHORT | ||||
| Control | – | <0.001 | – | 0.018 |
| Mild or No Sx | −0.1392 | −0.1368 | ||
| Severe acute Sx | −0.2144 | −0.0858 | ||
| MIS-C | −0.2762 | −0.1052 | ||
| Race/Ethnicity | ||||
| Caucasian | – | 0.042 | – | 0.981 |
| Black | 0.0734 | −0.0125 | ||
| Hispanic | −0.0428 | −0.0084 | ||
| Unknown | 0.0029 | −0.0312 | ||
| Presence LpZ | −0.2172 | <0.001 | 0.0042 | 0.936 |
The variables listed were analyzed in both univariate and multivariate regression and the estimates and p-values listed. Significant p-values are bolded. In the final multiply adjusted model, ApoA-I and the Cohort (grouped by symptom severity) explain 48% of the variance in HDL cholesterol effux capacity.
ApoA-I, apolipoprotein A-I; HDL, high density lipoprotein; Sx, symptoms; LpZ, lipoprotein Z, MIS-C, multisystem inflammatory syndrome of children.