TABLE 1.
Baseline characteristics, vital signs, laboratory parameters and statistic results of mimic-IIV patients with HF combined with hypertension.
| Variables | Total (n = 3458) | Survival (n = 2999) | Death (n = 459) | p |
| Gender, n (%) | 0.032 | |||
| 0 | 1756 (51) | 1501 (50) | 255 (56) | |
| 1 | 1702 (49) | 1498 (50) | 204 (44) | |
| Age, Median (Q1, Q3) | 75 (65, 84) | 74 (64, 83) | 80 (70, 87) | <0.001 |
| Ethnicity, n (%) | 0.005 | |||
| 0 | 923 (27) | 775 (26) | 148 (32) | |
| 1 | 2535 (73) | 2224 (74) | 311 (68) | |
| Weight, Median (Q1, Q3) | 79.5 (66.3, 95.9) | 80 (67.1, 96.95) | 74.2 (60.65, 91.1) | <0.001 |
| Hematocrit, Median (Q1, Q3) | 33.6 (28.8, 38.3) | 33.4 (28.6, 38.3) | 34.5 (29.8, 38.45) | 0.011 |
| Hemoglobin, Median (Q1, Q3) | 11 (9.4, 12.6) | 11 (9.4, 12.6) | 11.3 (9.8, 12.5) | 0.261 |
| Platelets, Median (Q1, Q3) | 202 (152, 266) | 202 (151, 264) | 210.5 (163.5, 291) | 0.003 |
| wbc, Median (Q1, Q3) | 10.8 (7.9, 14.8) | 10.55 (7.8, 14.6) | 12 (8.3, 16.45) | <0.001 |
| mch, Median (Q1, Q3) | 30.1 (28.6, 31.5) | 30.1 (28.6, 31.5) | 30.1 (28.4, 31.4) | 0.392 |
| mchc, Median (Q1, Q3) | 33 (31.9, 34) | 33.1 (32, 34.1) | 32.7 (31.5, 33.6) | <0.001 |
| mcv, Median (Q1, Q3) | 91 (87, 95) | 91 (87, 95) | 92 (87, 97) | 0.001 |
| rbc, Median (Q1, Q3) | 3.69 (3.16, 4.25) | 3.69 (3.14, 4.25) | 3.73 (3.27, 4.29) | 0.178 |
| rdw, Median (Q1, Q3) | 14.4 (13.6, 15.6) | 14.3 (13.55, 15.45) | 14.9 (13.8, 16.4) | <0.001 |
| aniongap, Median (Q1, Q3) | 14 (12, 17) | 14 (12, 16) | 16 (13, 19) | <0.001 |
| Bicarbonate, Median (Q1, Q3) | 24 (22, 27) | 24 (22, 27) | 24 (20, 27) | 0.002 |
| Bun, Median (Q1, Q3) | 21 (15, 29) | 20 (15, 28) | 27 (18.5, 39) | <0.001 |
| Calcium, Median (Q1, Q3) | 8.5 (8.1, 8.9) | 8.5 (8.1, 8.9) | 8.5 (7.9, 8.9) | 0.014 |
| Chloride, Median (Q1, Q3) | 104 (99, 108) | 104 (100, 108) | 102 (98, 106) | <0.001 |
| Creatinine, Median (Q1, Q3) | 1 (0.8, 1.3) | 1 (0.8, 1.2) | 1.2 (0.8, 1.6) | <0.001 |
| Sodium, Median (Q1, Q3) | 139 (136, 141) | 139 (136, 141) | 138 (135, 141) | 0.027 |
| Potassium, Median (Q1, Q3) | 4.2 (3.8, 4.6) | 4.1 (3.8, 4.6) | 4.2 (3.8, 4.8) | 0.001 |
| inr, Median (Q1, Q3) | 1.3 (1.1, 1.5) | 1.3 (1.1, 1.5) | 1.3 (1.1, 1.8) | <0.001 |
| pt, Median (Q1, Q3) | 14.2 (12.6, 16.9) | 14.1 (12.5, 16.7) | 14.7 (12.8, 19.5) | <0.001 |
| ptt, Median (Q1, Q3) | 31.5 (27.6, 38.2) | 31.4 (27.5, 37.75) | 32.2 (28.2, 40.65) | 0.005 |
| ck.cpk, Median (Q1, Q3) | 122 (82, 179) | 123 (83.5, 180) | 112.5 (71.5, 163) | <0.001 |
| ck.mb, Median (Q1, Q3) | 5 (3.5, 6) | 5 (3.5, 6) | 5 (3, 7) | 0.394 |
| Tn.T, Median (Q1, Q3) | 0.35 (0.29, 0.51) | 0.35 (0.29, 0.5) | 0.4 (0.27, 0.63) | 0.004 |
| Npro.BNP, Median (Q1, Q3) | 2526.5 (1188.5, 4441) | 2397 (1156.75, 4348.25) | 3339 (1553.5, 4960.25) | <0.001 |
| heart.rate, Median (Q1, Q3) | 84 (74, 97) | 84 (74, 96) | 87 (76, 102) | <0.001 |
| sbp, Median (Q1, Q3) | 123 (106, 139) | 123 (106, 140) | 123 (105, 139) | 0.538 |
| dbp, Median (Q1, Q3) | 64 (53, 76) | 64 (54, 76) | 64 (53, 77) | 0.75 |
| mbp, Median (Q1, Q3) | 80 (70, 93) | 80 (70, 93) | 78 (67, 92) | 0.099 |
| resp.rate, Median (Q1, Q3) | 18 (15, 22) | 18 (15, 22) | 20 (16, 24) | <0.001 |
| Temperature, Median (Q1, Q3) | 36.67 (36.33, 37) | 36.67 (36.33, 37) | 36.61 (36.22, 36.94) | 0.211 |
| spo2, Median (Q1, Q3) | 98 (95, 100) | 98 (96, 100) | 98 (95, 100) | <0.001 |
| Glucose, Median (Q1, Q3) | 134 (109, 173) | 133 (109, 169) | 144 (113, 193.5) | <0.001 |
| myocardial.infarct, n (%) | 0.89 | |||
| 0 | 2394 (69) | 2078 (69) | 316 (69) | |
| 1 | 1064 (31) | 921 (31) | 143 (31) | |
| congestive.heart.failure, n (%) | 0.005 | |||
| 0 | 897 (26) | 803 (27) | 94 (20) | |
| 1 | 2561 (74) | 2196 (73) | 365 (80) | |
| peripheral.vascular.disease, n (%) | 0.09 | 0.09 | ||
| 0 | 2900 (84) | 2528 (84) | 372 (81) | |
| 1 | 558 (16) | 471 (16) | 87 (19) | |
| cerebrovascular.disease, n (%) | <0.001 | |||
| 0 | 2912 (84) | 2551 (85) | 361 (79) | |
| 1 | 546 (16) | 448 (15) | 98 (21) | |
| Dementia, n (%) | 0.579 | |||
| 0 | 3327 (96) | 2888 (96) | 439 (96) | |
| 1 | 131 (4) | 111 (4) | 20 (4) | |
| chronic.pulmonary.disease, n (%) | 0.294 | |||
| 0 | 2152 (62) | 1877 (63) | 275 (60) | |
| 1 | 1306 (38) | 1122 (37) | 184 (40) | |
| rheumatic.disease, n (%) | 0.654 | |||
| 0 | 3288 (95) | 2854 (95) | 434 (95) | |
| 1 | 170 (5) | 145 (5) | 25 (5) | |
| peptic.ulcer.disease, n (%) | 0.118 | |||
| 0 | 3383 (98) | 2939 (98) | 444 (97) | |
| 1 | 75 (2) | 60 (2) | 15 (3) | |
| diabetes.without.cc, n (%) | 0.39 | |||
| 0 | 2332 (67) | 2031 (68) | 301 (66) | |
| 1 | 1126 (33) | 968 (32) | 158 (34) | |
| diabetes.with.cc, n (%) | 0.291 | |||
| 0 | 3216 (93) | 2795 (93) | 421 (92) | |
| 1 | 242 (7) | 204 (7) | 38 (8) | |
| Paraplegia, n (%) | <0.001 | |||
| 0 | 3343 (97) | 2914 (97) | 429 (93) | |
| 1 | 115 (3) | 85 (3) | 30 (7) | |
| renal.disease, n (%) | 0.142 | |||
| 0 | 3375 (98) | 2932 (98) | 443 (97) | |
| 1 | 83 (2) | 67 (2) | 16 (3) | |
| Aids, n (%) | 0.048 | |||
| 0 | 3455 (100) | 2998 (100) | 457 (100) | |
| 1 | 3 (0) | 1 (0) | 2 (0) | |
| mechvent, n (%) | <0.001 | |||
| 0 | 1247 (36) | 1131 (38) | 116 (25) | |
| 1 | 2211 (64) | 1868 (62) | 343 (75) | |
| uo.rt.24 h, Median (Q1, Q3) | 1.13 (0.74, 1.55) | 1.15 (0.78, 1.57) | 0.9 (0.56, 1.4) | <0.001 |
| rrt, n (%) | <0.001 | |||
| 0 | 3424 (99) | 2979 (99) | 445 (97) | |
| 1 | 34 (1) | 20 (1) | 14 (3) | |
| Hyperlipidemia, n (%) | <0.001 | |||
| 0 | 1633 (47) | 1378 (46) | 255 (56) | |
| 1 | 1825 (53) | 1621 (54) | 204 (44) | |
| atrialfibrillation, n (%) | <0.001 | |||
| 0 | 1776 (51) | 1576 (53) | 200 (44) | |
| 1 | 1682 (49) | 1423 (47) | 259 (56) | |
| charlson.comorbidity.index, Median (Q1, Q3) | 6 (5, 7) | 6 (5, 7) | 6 (5, 8) | <0.001 |
| lods, Median (Q1, Q3) | 4 (2, 6) | 4 (2, 6) | 7 (4, 10) | <0.001 |
| sapsii, Median (Q1, Q3) | 35 (29, 43) | 35 (28, 42) | 42 (34, 53) | <0.001 |
| oasis, Median (Q1, Q3) | 32 (26, 39) | 31 (26, 38) | 39 (32, 46) | <0.001 |
| f.sofa, Median (Q1, Q3) | 4 (2, 7) | 4 (2, 7) | 6 (4, 9) | <0.001 |