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. 2022 Oct 12;16:1018387. doi: 10.3389/fnins.2022.1018387

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Copyright © 2022 Yi, Wang, Yang, Huang, Liu, Chen, Zhang, Zhao, Li, Fang and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Brain regions with decreased ReHo (FWE corrected) in the first-episode MDD patients after taVNS are superimposed on a T1W template (first-episode MDD patients before and after treatment, paired-sample T-test). These regions included the left/right median cingulate cortex, the left precentral gyrus, the left postcentral gyrus, the right calcarine, the left supplementary motor area, the left paracentral lobule, and the right lingual gyrus with decreased ReHo after taVNS. The color bar signifies the T-value of the group analysis.