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. 2022 Oct 12;16:952204. doi: 10.3389/fnins.2022.952204

TABLE 5.

Descriptive statistics for participants with baseline data only vs. baseline and longitudinal data.

Participant characteristics Participants with baseline data only (N = 130) Participants with baseline + longitudinal data (N = 292) Chi-squared t-value P-value
Baseline Age, in years, M ± SD 69.2 ± 11.7 75.9 ± 8.83 −4.45 0.00001
Sex, N (%) 0.98 0.321
 Male 66 (49.2%) 133 (33.9%)
 Female 64 (50.8%) 159 (54.5%)
Race 1.09 0.580
 White 96 (73.8%) 212 (70.5%)
 Black 28 (21.5%) 69 (22.2%)
 Other 6 (4.6%) 23 (7.2%)
Baseline educational attainment (in years), M ± SD 17.5 ± 2.20 17.8 ± 2.52 −1.58 0.115
Baseline BMI, M ± SD 27.5 ± 4.62 26.6 ± 4.04 1.47 0.144
Baseline CES-D Score,a M ± SD 3.91 ± 4.50 3.72 ± 4.26 0.35 0.730
Baseline use of sleep medication,b N (%) 0.18 0.671
 No 105 (84.0%) 250 (85.6%)
 Yes 20 (16.0%) 42 (14.4%)
Baseline cardiovascular disease risk factors/morbidity, N (%) 6.70 0.010
 No 72 (55.0%) 122 (41.8%)
 Yes 59 (45.0%) 170 (58.2%)
Baseline smoking status,b,c N (%) 0.392
 Never smoked or quit > 10 years ago 122 (95.3%) 285 (98.3%)
 Current smoker or quit < 10 years ago 6 (4.7%) 5 (1.7%)
APOE Carrier Status,b n (%) 0.34 0.562
 APOE e4− 85 (75.5%) 206 (73.0%)
 APOE e4+ 27 (22.5%) 76 (27.0%)
Baseline CRARs, M ± SD
 Amplitude 2.18 ± 0.38 2.13 ± 0.40 0.81 0.420
 Mesor 3.22 ± 0.39 3.22 ± 0.40 −0.46 0.648
 Acrophase 14.8 ± 1.04 14.7 ± 1.17 1.21 0.228
 Relative amplitude 0.78 ± 0.08 0.77 ± 0.65 1.47 0.143
 Intradaily stability 0.11 ± 0.32 0.11 ± 0.33 0.19 0.849
 Interdaily variability 0.32 ± 0.10 0.33 ± 0.11 −0.41 0.684
 L5 time 1.54 ± 1.20 1.51 ± 1.37 0.11 0.917
 M10 time 9.26 ± 1.28 8.97 ± 1.45 1.81 0.071
Cognitive outcomes, M ± SD
 Verbal memory 0.11 ± 1.01 −0.08 ± 0.97 1.61 0.109
 Executive function 0.12 ± 0.89 −0.19 ± 0.72 2.17 0.031
 Attention 0.13 ± 0.96 −0.16 ± 0.77 1.95 0.053
 Language 0.11 ± 0.98 −0.11 ± 0.77 1.56 0.120
 Visuospatial skills 0.22 ± 0.86 −0.13 ± 0.77 3.19 0.002

aCES-D, Center for Epidemiologic Studies Depression Scale score without the sleep item.

bPercentages based on participants with complete data.

cFisher’s test was used to determine differences in smoking status between those with baseline data only vs. longitudinal data. M, mean; SD, standard deviation.