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. 2022 Oct 12;12:1008484. doi: 10.3389/fonc.2022.1008484

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Copyright © 2022 Lazcano, Barreto, Salazar, Carapeto, Traweek, Leung, Gite, Mehta, Ingram, Wani, Vu, Parra, Lu, Zhou, Witt, Cope, Thirasastr, Lin, Scally, Conley, Ratan, Livingston, Zarzour, Ludwig, Araujo, Ravi, Patel, Benjamin, Wargo, Wistuba, Somaiah, Roland, Keung, Solis, Wang, Lazar and Nassif

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Correlation Plots of Immune Biomarkers Studied in (A) Primary, (B) Recurrent, and (C) Metastatic UPS. Correlation plots displaying only the statistically significant correlations between tumor-associated immune cells, immune checkpoints and adenosine pathway biomarkers in (A) primary, (B) recurrent, and (C) metastatic samples. The colors of the circles are representative of the Spearman correlation with the scale represented at the bottom of the plots. The size of the circles indicate the significance level of the correlation, with larger circles representing lower p-values.