Table 3.
Immune biomarkers associated with lymphoid aggregates.
| Type of sample | Immune biomarkers (cells/mm2) | With LA | Without LA | |||
|---|---|---|---|---|---|---|
| n | Median (min, max) | n | Median (min, max) | p-value* | ||
| Primary | IDO1 | 10 | (0,10.13) | 32 | 0 (0,0.53) | 0.019 |
| Recurrent | CD3 | 4 | 884 (457, 2190) | 20 | 270 (12.7, 1530) | 0.011 |
| ICOS | 4 | 56.8 (32.4, 78.1) | 19 | 1.17 (0, 63.1) | <.001 | |
| OX40 | 4 | 2.23 (0, 4.01) | 19 | 0 (0, 3.24) | 0.020 | |
| CD163 | 4 | 3743 (3237, 4081) | 20 | 2735 (689, 4348) | 0.029 | |
| Metastatic | CD3 | 7 | 1006 (112, 1697) | 16 | 250 (27.8, 2145) | 0.033 |
*Wilcoxon rank-sum exact test.
Bold values indicate significant p-value.