Table 3. GDB-13 Cumulative Subset Sizes and Molecule Removal Criteria.

cumulated subset	subset size (molecules)	cumulative criteria
AB	635,647,478	no cyclic or acyclic HetHet bonds
ABC	441,084,370	stable FG
ABCD	277,628,675	no cyclic C=C or C≡C bonds
ABCDE	140,606,518	no acyclic C=C or C≡C bonds
ABCDEF	43,729,989	no small rings
ABCDEFG	12,899,741	fragment-like
ABCDEFGH	1,470,284	scaffold-like