Table 4. Estimated dietary exposure to aflatoxins and attributable cases of HCC in Nigeria and Malaysia.
| Country | Type of sample analysed | Variables | Aflatoxins levels (ng/gm) | Calculated DERA (ng/kgbw/day) | Calculated HCC per 100,000/year | % Incidence of the HCC per 100,000 |
|---|---|---|---|---|---|---|
| Nigeria | Rice | Mean | 29.64 | 50.08 | 4.13 | 57.94 |
| Min | 5.1 | 8.62 | 0.71 | 9.97 | ||
| Max | 81.8 | 138.20 | 11.40 | 159.91 | ||
| Wheat | Mean | 46.36 | 42.33 | 3.49 | 48.98 | |
| Min | 1.4 | 1.28 | 0.11 | 1.48 | ||
| Max | 93.6 | 57.49 | 4.74 | 66.52 | ||
| Maize | Mean | 28.38 | 28.38 | 2.34 | 32.84 | |
| Min | 9.4 | 9.40 | 0.78 | 10.88 | ||
| Max | 49.8 | 49.80 | 4.11 | 57.62 | ||
| Peanut | Mean | 37.52 | 23.04 | 1.90 | 26.66 | |
| Min | 1.5 | 0.92 | 0.08 | 1.07 | ||
| Max | 87.3 | 53.62 | 4.42 | 62.04 | ||
| Malaysia | Rice | Mean | 6.52 | 11.02 | 0.28 | 5.62 |
| Min | 4.9 | 8.28 | 0.21 | 4.22 | ||
| Max | 11.9 | 20.11 | 0.50 | 10.26 | ||
| Wheat | Mean | 28.3 | 10.75 | 0.27 | 5.49 | |
| Min | 14.4 | 5.47 | 0.14 | 2.79 | ||
| Max | 71.15 | 27.03 | 0.68 | 13.79 | ||
| Maize | Mean | 15.54 | 5.90 | 0.15 | 3.01 | |
| Min | 4.1 | 1.56 | 0.04 | 0.79 | ||
| Max | 26.7 | 10.14 | 0.25 | 5.18 | ||
| Peanut | Mean | 16.42 | 10.08 | 0.25 | 5.15 | |
| Min | 8.6 | 5.28 | 0.13 | 2.69 | ||
| Max | 24.8 | 15.23 | 0.38 | 7.77 |
Note:
– Min and Max are the minimum and maximum levels of aflatoxins in the samples, respectively.
– Calculated DERA (ng/kg BW/day) was computed as:
– Level of aflatoxins in food (ng/g) × Daily food intake per person (g/day) / Average bogy weight of an adult in the population (kgbw)(2) [75]
– Calculated HCC per 100,000/year was computed as:
– Estimated DERA (ng/KgBw/day) × Average cancer potency in the population (3) 75
– % Incidence of the HCC per 100,000 was computed as:
– Attributable HCC per 100,000/year / Average liver cancer incidence in the population × 100 (4) 75