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Pedigrees of two FALS patients and evolutionary conservation of mutated KIF1A amino acids. a Pedigrees of patients P4 and P9. Arrow, proband; square, man; circle, woman; slashed symbol, deceased; filled symbol, affected; empty symbol, unaffected. b Evolutionary conservation of altered amino acids of KIF1A associated with ALS. AA number, amino acid number of human KIF1A protein
