Table 5.
Logistic regression analysis of preoperative factors in patients with and without diabetes remission 1-year after surgery
| Characteristic | Unadjusted OR (95% CI) | p-value | Adjusted OR (95% CI) * | p-value |
|---|---|---|---|---|
| Female (male = ref) | 0.79 (0.57–1.12) | 0.194 | 0.68 (0.45–1.02) | 0.064 |
| Age on day of surgery (for each year) | 0.95 (0.94–0.96) | < 0.001 | 0.97 (0.95–0.98) | < 0.001 |
| BMI (kg/m2) (for each 1 unit) | 1.05 (1.03–1.08) | < 0.001 | 1.04 (1.01–1.07) | 0.003 |
| Diabetes duration (for each year) | 0.86 (0.84–0.88) | < 0.001 | 0.92 (0.89–0.94) | < 0.001 |
| Insulin use | 0.16 (0.12–0.22) | < 0.001 | 0.28 (0.19–0.42) | < 0.001 |
| Number of oral antidiabetic medications before surgery | ||||
|
0 1 2 ≥3 |
1 1.11 (0.59–2.09) 1.04 (0.47–2.29) 0.45 (0.15–1.31) |
0.739 0.923 0.141 |
1 1.06 (0.58–1.94) 0.96 (0.45–2.07) 0.58 (0.15–2.17) |
0.857 0.924 0.418 |
| Type of surgeries | ||||
|
RYGB OAGB SG |
1 0.93 (0.68–1.26) 0.76 (0.51–1.13) |
0.642 0.173 |
1 0.84 (0.58–1.22) 0.79 (0.48–1.30) |
0.354 0.357 |
| Fasting blood sugar (mg/dl) (for each 1 mg/dl) | 0.99 (0.98–0.99) | < 0.001 | 0.995 (0.991–0.998) | 0.001 |
| HbA1c (for each 1%) | 0.64 (0.59–0.69) | < 0.001 | 0.78 (0.69–0.87) | < 0.001 |
| Total cholesterol (mg/dl) | 1.00 (0.995–1.01) | 0.835 | 1.003 (0.995–1.012) | 0.445 |
| Triacylglycerol (mg/dl) | 1.00 (0.999–1.001) | 0.763 | 0.998 (0.997-1.00) | 0.084 |
| HDL-cholesterol (mg/dl) | 1.001 (0.989–1.014) | 0.852 | 1.00 (0.998–1.002) | 0.997 |
| LDL- cholesterol (mg/dl) | 0.999 (0.995–1.002) | 0.410 | 0.995 (0.986–1.004) | 0.282 |
| AST (IU/L) | 0.997 (0.99–1.004) | 0.391 | 1.00 (0.986–1.013) | 0.943 |
| ALT (IU/L) | 0.998 (0.99–1.01) | 0.265 | 0.998 (0.988–1.008) | 0.674 |
| Systolic blood pressure, mm Hg | 0.999 (0.991–1.007) | 0.843 | 1.006 (0.992–1.019) | 0.423 |
| Diastolic blood pressure, mm Hg | 1.003 (0.989–1.016) | 0.707 | 0.996 (0.974–1.018) | 0.725 |
| Obesity-related disease (no = ref) | ||||
|
Dyslipidemia Hypertension Cardiovascular Disease Hypothyroidism Sleep Apnea Asthma Fatty Liver |
1.06 (0.81–1.39) 1.02 (0.78–1.34) 1.11 (0.82–1.50) 0.83 (0.62–1.11) 0.83 (0.62–1.09) 1.42 (0.86–2.36) 0.96 (0.67–1.40) |
0.667 0.869 0.512 0.215 0.187 0.173 0.839 |
1.13 (0.79–1.60) 1.04 (0.73–1.47) 1.15 (0.76–1.72) 0.69 (0.48–1.02) 0.84 (0.58–1.21) 1.76 (0.94–3.32) 1.21 (0.76–1.93) |
0.504 0.834 0.508 0.168 0.339 0.079 0.417 |
| Family History of, (no = ref) | ||||
|
Obesity Hypertension Diabetes Dyslipidemia Fatty Liver |
0.42 (0.26–0.68) 1.34 (0.76–2.36) 0.75 (0.55–1.02) 0.90 (0.12–6.86) 1.14 (0.45–2.88) |
< 0.001 0.317 0.064 0.919 0.790 |
0.33 (0.19–0.56) 1.72 (0.82–3.64) 0.95 (0.65–1.39) 0.60 (0.12–3.01) 1.03 (0.44–1.78) |
< 0.001 0.154 0.813 0.537 0.731 |
* Multivariable logistic regression including all factors listed in the table