Table 6.
Logistic regression analysis of preoperative factors in patients with and without diabetes remission 3 years after surgery
| Characteristic | Unadjusted OR (95% CI) | p-value | Adjusted OR (95% CI) * | p-value |
|---|---|---|---|---|
| Female (male = ref) | 0.91 (0.58–1.40) | 0.657 | 0.71 (0.42–1.21) | 0.206 |
| Age on day of surgery (years) | 0.96 (0.94–0.98) | < 0.001 | 0.96 (0.94–0.99) | 0.003 |
| BMI (kg/m2) | 1.07 (1.04–1.11) | < 0.001 | 1.07 (1.03–1.11) | < 0.001 |
| Diabetes duration (years) | 0.88 (0.85–0.91) | < 0.001 | 0.896 (0.87–0.93) | < 0.001 |
| Insulin use | 0.17 (0.11–0.24) | < 0.001 | 4.679 (2.82–7.76) | < 0.001 |
| Number of oral antidiabetic medications before surgery | ||||
|
0 1 2 ≥3 |
1 0.94 (0.58–1.49) 0.61 (0.35–1.06) 0.49 (0.16–1.27) |
0.782 0.081 0.134 |
1 0.906 (0.49–1.65) 0.67 (0.33–1.37) 0.49 (0.13–1.84) |
0.747 0.272 0.295 |
| Type of surgeries | ||||
|
RYGB OAGB SG |
1 1.12 (0.76–1.66) 0.92 (0.54–1.58) |
0.571 0.770 |
1 1.01 (0.62–1.64) 0.96 (0.49–1.88) |
0.974 0.910 |
| Fasting blood sugar (mg/dl) | 0.989 (0.986–0.991) | < 0.001 | 0.992 (0.988–0.995) | < 0.001 |
| HbA1c (%) | 0.64 (0.58–0.71) | < 0.001 | 0.82 (0.71–0.96) | 0.010 |
| Total cholesterol (mg/dl) | 0.999 (0.996–1.002) | 0.593 | 1.01 (0.99–1.02) | 0.695 |
| Triacylglycerol (mg/dl) | 0.998 (0.997-1.00) | 0.202 | 0.999 (0.996–1.001) | 0.326 |
| HDL-cholesterol (mg/dl) | 1.01 (0.991–1.03) | 0.328 | 1.01 (0.98–1.03) | 0.617 |
| LDL- cholesterol (mg/dl) | 0.998 (0.994–1.003) | 0.479 | 0.997 (0.984–1.01) | 0.720 |
| AST (IU/L) | 0.997 (0.989–1.004) | 0.393 | 0.992 (0.978–1.005) | 0.221 |
| ALT (IU/L) | 0.996 (0.99–1.002) | 0.192 | 1.005 (0.988–1.022) | 0.582 |
| Systolic blood pressure, mm Hg | 1.00 (0.98–1.02) | 0.906 | 1.002 (0.983–1.022) | 0.807 |
| Diastolic blood pressure, mm Hg | 1.01 (0.95–1.03) | 0.158 | 1.021 (0.990–1.05) | 0.187 |
| Obesity-related disease (no = ref) | ||||
|
Dyslipidemia Hypertension Cardiovascular Disease Hypothyroidism Sleep Apnea Asthma Fatty Liver |
0.79 (0.55–1.13) 0.94 (0.65–1.36) 1.33 (0.88–2.01) 0.86 (0.58–1.27) 0.89 (0.61–1.31) 1.27 (0.64–2.55) 0.77 (0.45–1.31) |
0.190 0.761 0.175 0.443 0.564 0.496 0.334 |
0.66 (0.42–1.06) 0.85 (0.53–1.34) 1.39 (0.81–2.43) 0.70 (0.42–1.16) 1.001 (0.61–1.65) 1.49 (0.59–3.75) 1.38 (0.71–2.67) |
0.085 0.483 0.232 0.168 0.996 0.401 0.342 |
| Family History of, (no = ref) | ||||
|
Obesity Hypertension Diabetes Dyslipidemia Fatty Liver |
0.42 (0.26–0.68) 1.06 (0.58–1.93) 0.96 (0.67–1.04) 3.06 (0.40-23.39) 1.10 (0.64–1.92) |
< 0.001 0.859 0.829 0.280 0.727 |
0.46 (0.28–0.76) 1.43 (0.63–3.27) 1.45 (0.89–2.34) 1.16 (0.14–9.82) 1.38 (0.66–2.92) |
0.003 0.396 0.130 0.895 0.393 |
* Multivariable logistic regression including all factors listed in the table