Table 7.
Inhibition of cyclooxygenase-2 (COX-2) enzyme by the extracts of P. glauca and caperatic acid.
| Extract/Substance | Equivalent Concentration of Acetylsalicylic Acid [mg/mL] |
COX-2 Inhibition under Reaction Conditions [%] |
|---|---|---|
| DCM extract | na | na |
| Ace extract | 3.39 ± 0.01 e | 4.8 ± 1.0 d |
| MeOH extract | 18.64 ± 0.00 b | 26.2 ± 0.2 b |
| MeOH-H2O extract | 16.95 ± 0.01 d | 23.8 ± 0.2 c |
| H2O extract | 22.03 ± 0.02 a | 28.6 ± 0.3 a |
| Caperatic acid | 18.25 ± 0.02 c | 25.9 ± 0.1 b |
Mean values within a column with the same letter are not significantly different at p 0.05 using Duncan’s test. The first letter of the alphabet for the highest values, the next for statistically significant decreasing values. The mean values ± SD from at least n = 4 independent measurements are presented; na—not active.