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. 2022 Sep 20;10(10):2336. doi: 10.3390/biomedicines10102336

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effect of 2-Cl-4,5-MDMA and 3,4-MDPHP administration on plasma corticosterone levels in male and female rats. Corticosterone levels measured in plasma (expressed as nanograms per milliliter of plasma) of male and female rats at the end of the self-administration training. Data are expressed as mean ± SEM of values from 7 to 12 rats per group (males: saline, n = 7; 2-Cl-4,5-MDMA, n = 10; 3,4-MDPHP, n = 11; females: saline, n = 8; 2-Cl-4,5-MDMA, n = 12; 3,4-MDPHP, n = 8). * p < 0.001 and ** p < 0.0001 vs. the respective 3,4-MDPHP-treated group; ^# p < 0.01 and ^## p < 0.0001 vs. the respective female group; two-way ANOVA followed by Tukey’s multiple comparisons test.