| ROS | reactive oxygen species; |
| HCC | hepatic carcinogenesis; |
| HBV | hepatitis B virus; |
| HCV | hepatitis C virus; |
| ALD | alcohol-related liver disease; |
| NAFLD | nonalcoholic fatty liver disease; |
| NADPH | nicotinamide adenine dinucleotide phosphate hydrogen; |
| KC | Kupffer cells; |
| HSCs | hepatic stellate cells; |
| ECs | endothelial cells; |
| PRR | pattern recognition receptor; |
| DAMPs | damage-associated molecular patterns; |
| PAMPs | pathogen-associated molecular patterns; |
| HAMPs | homeostasis-altering molecular processes; |
| NOD | nucleotide-binding oligomerization domain; |
| NLRC | NOD-like receptor CARD domain containing; |
| NLRP | NOD-like receptor Pyrin domain containing; |
| TNFR | tumor necrosis factor receptor; |
| TLR | Toll-like receptors; |
| ECM | extracellular matrix; |
| TGF-β1 | transforming growth factor β1; |
| αSMA | α-smooth muscle actin; |
| BDL | bile duct ligation; |
| NASH | non-alcohol associated steatohepatitis; |
| HIF-1α | Hypoxia Inducible Factor 1α; |
| ET-1 | endothelin-1; |
| LSEC | liver sinusoidal endothelial cells; |
| DAAs | direct-acting antiviral agents; |
| HCC | hepatocellular carcinoma; |
| SVR | sustained virologic response; |
| FXR or NR1H4 | farnesoid receptor; |
| PKCf | Protein kinase C f; |
| ERK | Extracellular signal-regulated kinase; |
| VSMCs | Vascular Smooth Muscle Cells; |
| EGFR | epidermal growth factor receptor; |
| VEGF | vascular endothelial growth factor; |
| VEGFR2 | vascular endothelial growth factor receptor 2; |
| RTK | receptor tyrosine kinase; |
| GPCR | G protein-coupled receptors; |
| SRC | protooncogene tyrosine-protein kinase; |
| RAS | serine-threonine kinase; |
| PTEN | lipid tyrosine phosphatase; |
| PI3K | phosphoinositol 3-kinase; |
| mTOR | target of rapamycin; |
| HIF | hypoxia-inducible factors; |
| VEGF | vascular endothelial growth factor; |
| MMPs | matrix metalloproteinases; |
| HIFs | hypoxia-inducible transcription factors; |
| AMPK | AMP-activated protein kinase; |
| TSG | tumor-suppressor gene. |