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. 2022 Oct 16;11(10):2038. doi: 10.3390/antiox11102038
ROS reactive oxygen species;
HCC hepatic carcinogenesis;
HBV hepatitis B virus;
HCV hepatitis C virus;
ALD alcohol-related liver disease;
NAFLD nonalcoholic fatty liver disease;
NADPH nicotinamide adenine dinucleotide phosphate hydrogen;
KC Kupffer cells;
HSCs hepatic stellate cells;
ECs endothelial cells;
PRR pattern recognition receptor;
DAMPs damage-associated molecular patterns;
PAMPs pathogen-associated molecular patterns;
HAMPs homeostasis-altering molecular processes;
NOD nucleotide-binding oligomerization domain;
NLRC NOD-like receptor CARD domain containing;
NLRP NOD-like receptor Pyrin domain containing;
TNFR tumor necrosis factor receptor;
TLR Toll-like receptors;
ECM extracellular matrix;
TGF-β1 transforming growth factor β1;
αSMA α-smooth muscle actin;
BDL bile duct ligation;
NASH non-alcohol associated steatohepatitis;
HIF-1α Hypoxia Inducible Factor 1α;
ET-1 endothelin-1;
LSEC liver sinusoidal endothelial cells;
DAAs direct-acting antiviral agents;
HCC hepatocellular carcinoma;
SVR sustained virologic response;
FXR or NR1H4 farnesoid receptor;
PKCf Protein kinase C f;
ERK Extracellular signal-regulated kinase;
VSMCs Vascular Smooth Muscle Cells;
EGFR epidermal growth factor receptor;
VEGF vascular endothelial growth factor;
VEGFR2 vascular endothelial growth factor receptor 2;
RTK receptor tyrosine kinase;
GPCR G protein-coupled receptors;
SRC protooncogene tyrosine-protein kinase;
RAS serine-threonine kinase;
PTEN lipid tyrosine phosphatase;
PI3K phosphoinositol 3-kinase;
mTOR target of rapamycin;
HIF hypoxia-inducible factors;
VEGF vascular endothelial growth factor;
MMPs matrix metalloproteinases;
HIFs hypoxia-inducible transcription factors;
AMPK AMP-activated protein kinase;
TSG tumor-suppressor gene.