Figure 4.

(a) Platelet aggregation and representative aggregometer trace, (b) Thromboxane B₂ production, (c) soluble P-selectin levels, (d) soluble CD 40 ligand, (e) serum soluble NOX2-derived peptide (sNOX2-dp), (f) serum H₂O₂ in washed platelets (wPLTs) taken from HS (n = 5) pre-incubated with or without d-Glucose (d-Glu, 10 mM) and then stimulated with or without STC of collagen (0.25 μg/mL) in the presence or less of dapagliflozin (Dapa, 30 µM) or dulaglutide (Dula, 100 nmol/L) or negative control (NC). Data were expressed as mean ± SD; * p < 0.05, ** p < 0.01; *** p < 0.001.