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. 2022 Sep 21;10(10):2353. doi: 10.3390/biomedicines10102353

Table 4.

Comparison of the characteristics among standard oxygen therapy, high-flow nasal cannula, and continuous positive airway pressure.

Standard Oxygen Therapy High-Flow Nasal Cannula Continuous Positive Airway Pressure
Optimal gas conditioning / +++ +
Generation of positive end-expiratory pressure / + +++
Wash-out of nasopharyngeal dead space / +++ +
Improvement in mucociliary clearance / +++ /
Flow and oxygen concentration setting / +++ +++
Reduced breathing effort / ++ +++
Reduction in upper airway resistance / + +++
Patient’s comfort ++ + /

/ no effect; + low effect; ++ medium effect; +++ high effect.