Figure 10.

The proposed mechanism of PDGF signaling in the lens epithelial cells. The solid line indicates the known or published pathway and the dashed line represents proposed new pathway. In the figure, EGF denotes Epidermal growth factor, GPCR indicates G protein coupled receptor, PI3K indicates Phosphatidyl inositol-3-kinase, cPLA₂ denotes Cytosolic phospholipase 2, PL indicates Phospholipid, AA denotes Arachidonic acid, PKC indicates Protein kinase C, and ROS denotes Reactive oxygen species. Reprinted with permission from Chen et al., Molecular Vision (2007); Free Access [91].