Table 1.
Baseline of demographic and clinical characteristics.
| Parameter | Total Cohort | Sepsis | Septic Shock | p-Value * |
|---|---|---|---|---|
| Age (years) | 74 (58–80) |
60 (54–79.5) |
76.5 (60–80.75) |
0.28 |
| Gender n (%) female male |
12 (57%) 9 (43%) |
6 (86%) 1 (14%) |
6 (42%) 8 (58%) |
0.16 |
| Weight (kg) | 72.52 ± 19.40 | 71.14 ± 25.29 | 73.21 ± 16.80 | 0.85 |
| Height (cm) | 166.57 ± 9.61 | 163.57 ± 10.00 | 168.07 ± 9.41 | 0.34 |
| BMI (kg/m2) | 26.05 ± 6.46 | 26.45 ± 9.07 | 25.85 ± 5.10 | 0.87 |
| APACHE II score | 31.19 ± 4.19 | 30.43 ± 2.7 | 31.57 ± 4.82 | 0.5 |
| Predicted mortality APACHE II (%) | 83.73 ± 7.94 | 83.17 ± 5.72 | 84.02 ± 9.03 | 0.8 |
| SOFA score | 14 (12–15) |
13 (12–14.5) |
15 (13.25–15) |
0.28 |
| LOS in ICU (days) 28 d observed mortality n (%) ICU observed mortality n (%) 90 d observed mortality n (%) |
24.38 ± 15.67 7 (33%) 8 (38%) 8 (38%) |
22.29 ± 17.73 0 (0%) 0 (0%) 0 (0%) |
25.43 ± 15.13 7 (50%) 8 (57%) 8 (57%) |
0.70 0.032 0.018 0.018 |
| Septic focus n (%) Abdominal Others: pulmonary pelvinal lower extremity |
15 (71%) 6 (29%) 3 (14%) 2 (10%) 1 (5%) |
6 (86%) 1 (14%) 1 (14%) 0 0 |
9 (65%) 5 (35%) 2 (14%) 2 (14%) 1 (7%) |
0.34 |
| Duration of CytoSorb® application/patient (h) | 82.51 ± 18.02 | 80.74 ± 24.56 | 83.39 ± 14.79 | 0.8 |
| Number of CytoSorb® adsorbers/patient (n) | 5.10 ± 2.17 | 4.14 ± 2.12 | 5.57 ± 2.10 | 0.17 |
| ABP (L/kg) | 13.23 ± 1.71 | 13.52 ± 1.05 | 13.08 ± 1.98 | 0.52 |
| Level of sepsis (Sepsis-3) Sepsis Septic shock |
7 (33%) 14 (67%) |
0 14 |
7 0 |
|
| Lactate mmol/L | 2.27 (1.79–3.99) |
1.39 (1.29–1.71) |
3.75 (2.4–4.28) |
0.00002 # |
Legend: Age, height, weight, APACHE II, SOFA, LOS in ICU, Duration of CytoSorb® application and number of CytoSorb® adsorbers: Mean ± SD or median, ( ): IQR, all other values: Absolute number and percentage share, *: Statistical comparison between sepsis and septic shock, #: significant p-value: p < 0.05.