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. 2022 Oct 21;11(10):2080. doi: 10.3390/antiox11102080

Figure 4.

Figure 4

Effect of TGFβ2 on SMAD4 mitochondrial translocation and inhibition by αBC-ELP. hRPE cells were treated with TGFβ2 (10 ng/mL) for 24 h and double stained for mitochondria (Red) and SMAD4 (Green). SMAD4 mitochondrial translocation was observed in TGFβ2 treated cells (white arrow heads) which was inhibited by αBC-ELP at two different doses. Scale bar: 5 µm, Green: SMAD4, Red: Mitotracker, Blue, DAPI.