Figure 11.

Regulation of EMT- and MET-associated proteins by αBC-ELP in dispase-induced PVR in mice. The experimental protocol is shown in Figure 8a. Protein expression was measured by Western blot analysis (a). EMT-associated proteins (αSMA, Fibronectin and Vimentin) significantly increased with dispase treatment, and αBC-ELP treatment significantly inhibited their expression (b). MET-associated protein (E-cadherin) had no significant difference with αBC-ELP treatment, and αBC-ELP treatment did not alter the expression (b). Values are means ± SEM. N.S.: not significant, αBC-ELP: αB crystallin-Elastin-like peptide. * p < 0.05, ** p < 0.01. n = 3.