Table 4.

Activity of antimicrobial agents tested against 944 Klebsiella isolates from intra-abdominal infections.

Activity of antimicrobial agents tested against 944 Klebsiella isolates from intra-abdominal infections in the SENTRY program collected during 2019, 2020, and 2021
Organisms include: Klebsiella aerogenes (69), K. oxytoca (153), K. pneumoniae (693), K. variicola (29)
Antimicrobial Agent	Continent	Count	MIC50	MIC90	Range	CLSI			EUCAST
						S (%)	I (%)	R (%)	S (%)	I (%)	R (%)
Ertapenem	All	709	0.015	0.5	≤0.008 to >2	90.6	0.8	8.6	90.6	0	9.4
	Asia-W. Pacific	150	≤0.008	>2	≤0.008 to >2	88.0	1.3	10.7	88.0	0	12.0
	Europe	208	0.015	>2	≤0.008 to >2	83.2	0.5	16.3	83.2	0	16.8
	Latin America	56	0.015	1	≤0.008 to >2	89.3	1.8	8.9	89.3	0	10.7
	North America	295	0.015	0.12	≤0.008 to >2	97.3	0.7	2.0	97.3	0	2.7
Imipenem	All	944	≤0.12	1	≤0.12 to >8	93.0	0.5	6.5	93.5	0.7	5.7
	Asia-W. Pacific	213	≤0.12	1	≤0.12 to >8	92.5	0.5	7.0	93.0	0.0	7.0
	Europe	324	≤0.12	2	≤0.12 to >8	88.9	1.2	9.9	90.1	1.5	8.3
	Latin America	79	≤0.12	8	≤0.12 to >8	88.6	0.0	11.4	88.6	1.3	10.1
	North America	328	≤0.12	0.5	≤0.12 to >8	98.5	0.0	1.5	98.5	0.3	1.2
Meropenem	All	944	0.03	0.12	≤0.015 to >32	93.1	0.4	6.5	93.5	1.6	4.9
	Asia-W. Pacific	213	0.03	0.12	≤0.015 to >32	92.5	0.0	7.5	92.5	1.9	5.6
	Europe	324	0.03	4	≤0.015 to >32	89.2	0.6	10.2	89.8	2.8	7.4
	Latin America	79	0.03	4	≤0.015 to >32	88.6	1.3	10.1	89.9	1.3	8.9
	North America	328	0.03	0.03	≤0.015 to >32	98.5	0.3	1.2	98.8	0.3	0.9

Abbreviations (MIC50 and MIC90: the lowest concentration of the antibiotic at which 50 and 90% of the isolates were inhibited; CLSI: Clinical and Laboratory Standards Institute; EUCAST: European Committee on Antimicrobial Susceptibility Testing; S (%) percentage of susceptible pathogens, evidenced in green; I (%) percentace of pathogens with intermediate susceptibility, evidenced in yellow; R (%) percentage of resistant pathogens, evidenced in red).