Table 5.
Activity of antimicrobial agents tested against 1922 Escherichia isolates from intra-abdominal infections in the SENTRY program collected during 2019, 2020, and 2021 | |||||||||||
Organisms include: Escherichia coli (1921), E. marmotae (1) | |||||||||||
Antimicrobial Agent | Continent | Count | MIC50 | MIC90 | Range | CLSI | EUCAST | ||||
S (%) | I (%) | R (%) | S (%) | I (%) | R (%) | ||||||
Ertapenem | All | 1459 | ≤0.008 | 0.03 | ≤0.008 to >2 | 98.5 | 0.5 | 1.0 | 98.5 | 0 | 1.5 |
Asia-W. Pacific | 209 | ≤0.008 | 0.06 | ≤0.008 to >2 | 96.7 | 1.0 | 2.4 | 96.7 | 0 | 3.3 | |
Europe | 510 | ≤0.008 | 0.03 | ≤0.008 to >2 | 99.0 | 0.8 | 0.2 | 99.0 | 0 | 1.0 | |
Latin America | 178 | ≤0.008 | 0.06 | ≤0.008 to >2 | 99.4 | 0.0 | 0.6 | 99.4 | 0 | 0.6 | |
North America | 562 | ≤0.008 | 0.03 | ≤0.008 to >2 | 98.4 | 0.4 | 1.2 | 98.4 | 0 | 1.6 | |
Imipenem | All | 1922 | ≤0.12 | ≤0.12 | ≤0.12 to >8 | 99.2 | 0.2 | 0.7 | 99.3 | 0.2 | 0.5 |
Asia-W. Pacific | 336 | ≤0.12 | 0.25 | ≤0.12 to >8 | 98.2 | 0.0 | 1.8 | 98.2 | 0.0 | 1.8 | |
Europe | 775 | ≤0.12 | ≤0.12 | ≤0.12 to 4 | 99.6 | 0.3 | 0.1 | 99.9 | 0.1 | 0.0 | |
Latin America | 249 | ≤0.12 | 0.25 | ≤0.12 to 8 | 98.4 | 0.0 | 1.6 | 98.4 | 0.8 | 0.8 | |
North America | 562 | ≤0.12 | ≤0.12 | ≤0.12 to >8 | 99.5 | 0.2 | 0.4 | 99.6 | 0.0 | 0.4 | |
Meropenem | All | 1922 | ≤0.015 | 0.03 | ≤0.015 to >32 | 99.3 | 0.2 | 0.6 | 99.4 | 0.2 | 0.4 |
Asia-W. Pacific | 336 | ≤0.015 | 0.03 | ≤0.015 to >32 | 98.2 | 0.0 | 1.8 | 98.2 | 0.6 | 1.2 | |
Europe | 775 | ≤0.015 | 0.03 | ≤0.015 to 16 | 99.9 | 0.0 | 0.1 | 99.9 | 0.0 | 0.1 | |
Latin America | 249 | ≤0.015 | 0.03 | ≤0.015 to 32 | 98.4 | 0.8 | 0.8 | 99.2 | 0.0 | 0.8 | |
North America | 562 | ≤0.015 | 0.03 | ≤0.015 to >32 | 99.5 | 0.2 | 0.4 | 99.6 | 0.2 | 0.2 |
Abbreviations (MIC50 and MIC90: the lowest concentration of the antibiotic at which 50 and 90% of the isolates were inhibited; CLSI: Clinical and Laboratory Standards Institute; EUCAST: European Committee on Antimicrobial Susceptibility Testing; S (%) percentage of susceptible pathogens, evidenced in green; I (%) percentace of pathogens with intermediate susceptibility, evidenced in yellow; R (%) percentage of resistant pathogens, evidenced in red).