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. 2022 Oct 7;11(10):1990. doi: 10.3390/antiox11101990

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Hepatic markers of the endoplasmic reticulum stress and mitochondrial dynamics in control and BTBR mice. Percentage and length of mitochondria detected by histological analyses (A). Hepatic expression levels of endoplasmic reticulum stress markers: Binding Immunoglobulin Protein (BIP) and phosphorylated eukaryotic translation initiation factor 2A (pEIF2α), as ratio pEIF2α/EIF2α (B). Expression levels of markers of mitochondrial dynamics: fusion-related proteins mitofusin 1 (MFN1), mitofusin 2 (MFN2) and optic atrophy protein (OPA1) (C), and fission-related dynamin-related protein (DRP1) and fission 1 protein (FIS1) (D). (n = 4 animal/group). * p < 0.05, *** p < 0.001, BTBR vs. Control (CTR).