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. 2022 Sep 20;10(10):2334. doi: 10.3390/biomedicines10102334

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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miRNA interactions with lncRNA and mRNA of BEAS-2B-Cr(VI). The miRNA interactions with mRNAs that have been up- and down-regulated are shown in (A,B). miRNA interactions with lncRNAs that have been up- and down-regulated are shown in (C,D), respectively. (E) The shared miRNAs in array profile and predictably interacting with DE lncRNAs and mRNAs in oncogenic and tumor suppressor activities. Triple networks comprising lncRNA/miRNA/mRNA in oncogenic and tumor suppressor activities are shown in (F,G), respectively. The three-color system of green, red, and blue represents lncRNA, miRNA, and mRNA, respectively. Gene ID of mRNA and lncRNA (last 6 digits only) was used in each node of the network.