Table 3.
The changes of serum biomarkers in patients with COVID-19.
| Day 1 | Day 7 | Day 28 | p-Value | |
|---|---|---|---|---|
| TNFα, pg/mL | 21.9 (17.2–26.6) | 24.2 (19.2–27.6) | 19.5 (16.6–23.1) | p < 0.001 * |
| IL-1β, pg/mL | 21.2 (12.5–26.9) | 23.6 (15–28.4) | 18.3 (12.5–24.7) | p < 0.001 # |
| Pentraxin 3, pg/mL | 6643 (3852–11,148) | 3369 (2179–5007) | 1839 (1111–2597) | p < 0.001 * |
| Chemerin, pg/mL | 8916 (6661–10,773) | 7359 (5705–9533) | 9324 (7371–11,033) | p < 0.001 # |
| Adiponectin, ng/mL | 6559 (4640–13,041) | 7134 (5170–14,854) | 8455 (6080–19,191) | p < 0.001 * |
| Resistin, pg/mL | 21,600 (14,123–29,587) | 5586 (11,257–21,676) | 11,629 (8415–15,690) | p < 0.001 * |
| Angiopoietin2, pg/mL | 1502 (1070–2247) | 1256 (907–1678) | 1662 (1173–2125) | p < 0.001 # |
| Leptin, pg/mL | 1824 (989–3981) | 1569 (858–3153) | 1372 (820–2652) | p < 0.001 * |
The Friedman ANOVA by ranks with post-hoc analysis. The results are shown as medians (IQR). p < 0.001 for the difference between the mean ranks; p < 0.05 for post-hoc analysis, * day 1 vs. day 7, day 7 vs. day 28, day 1 vs. day 28; # day 1 vs. day 7, day 7 vs. day 28. COVID-19, coronavirus disease 2019; TNFα, tumor necrosis factor alfa; IL-1β, interleukin 1 beta.