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. 2022 Oct 13;10(10):2568. doi: 10.3390/biomedicines10102568

Table 5.

Toxicity profile and cosmesis for the 26 Gy in 5 fractions over 1 week schedule.

Parameter Grade N (%)
End of Treatment 3 Weeks after RT 6 Months after RT
G0 G1 G2 G3 G4–G5 G0 G1 G2 G3 G4–G5 G0 G1 G2 G3 G4–G5
Erythema 47 (79.7) 11 (18.6) 1 (1.7) 0 (0.0) 0 (0.0) 31 (68.9) 11 (24.4) 3 (6.7) 0 (0.0) 0 (0.0) 11 (91.7) 1 (8.3) 0 (0.0) 0 (0.0) 0 (0.0)
Skin ulceration 59 (100.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 45 (100.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 12 (100.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
Skin induration 47 (79.7) 11 (18.6) 1 (1.7) 0 (0.0) 0 (0.0) 32 (71.1) 11 (24.4) 2 (4.4) 0 (0.0) 0 (0.0) 4 (33.3) 6 (50.0) 2 (16.7) 0 (0.0) 0 (0.0)
Atrophy 59 (100.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 43 (95.6) 2 (4.4) 0 (0.0) 0 (0.0) 0 (0.0) 11 (91.7) 1 (8.3) 0 (0) 0 (0.0) 0 (0.0)
Skin hyperpigmentation 59 (100.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 26 (57.8) 18 (40.0) 1 (2.2) 0 (0.0) 0 (0.0) 8 (66.7) 4 (33.3) 0 (0) 0 (0.0) 0 (0.0)
Skin hypopigmentation 59 (100.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 44 (97.8) 0 (0.0) 1 (2.2) 0 (0.0) 0 (0.0) 12 (100.0) 0 (0.0) 0 (0) 0 (0.0) 0 (0.0)
Teleangiectasiae 59 (100.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 44 (97.8) 0 (0.0) 1 (2.2) 0 (0.0) 0 (0.0) 10 (83.3) 2 (16.7) 0 (0) 0 (0.0) 0 (0.0)
Oedema 56 (94.9) 3 (5.1) 0 (0.0) 0 (0.0) 0 (0.0) 40 (88.9) 5 (11.1) 0 (0.0) 0 (0.0) 0 (0.0) 12 (100.0) 0 (0.0) 0 (0) 0 (0.0) 0 (0.0)
Pruritus 56 (94.9) 2 (3.4) 1 (1.7) 0 (0.0) 0 (0.0) 34 (75.6) 10 (22.2) 1 (2.2) 0 (0.0) 0 (0.0) 12 (100.0) 0 (0.0) 0 (0) 0 (0.0) 0 (0.0)
Pain 55 (93.2) 4 (6.8) 0 (0.0) 0 (0.0) 0 (0.0) 36 (80.0) 8 (17.8) 1 (2.2) 0 (0.0) 0 (0.0) 11 (91.7) 0 (0.0) 1 (8.3) 0 (0.0) 0 (0.0)
Cosmesis
Definition Poor Fair Good Excellent Poor Fair Good Excellent Poor Fair Good Excellent
0 (0.0) 1 (1.7) 23 (39.0) 35 (59.3) 0 (0.0) 1 (2.2) 14 (31.2) 30 (66.6) 0 (0.0) 1 (8.3) 4 (33.3) 7 (58.4)

Legend: N°, number; RT, radiation therapy.