Table 1.
The effect of EB367 on proliferation rate (% of control), cell membrane damage and DNA fragmentation of MCF-7 cells in vitro. Data presented as mean ± standard deviation (SD) of 3 independent experiments.
| Concentration of EB367 | Relative Cell Number [Mean Value ± SD] | Percentage of Cells with Damaged Cell Membrane [Mean Value ± SD] | Percentage of Cells with Fragmented DNA [Mean Value ± SD] |
|---|---|---|---|
| 0 µg/mL (control) | 100 ± 7 | 3.9 ± 1.9 | 1.3 ± 0.6 |
| 25 µg/mL | 45 ± 9 ** | 5.0 ± 1.0 | 2.7 ± 1.2 |
| 50 µg/mL | 43 ± 6 ** | 7.8 ± 1.6 * | 3.1 ± 0.9 |
* p < 0.05, ** p < 0.01 vs. control.