Figure 8.

Activity of neighboring synapses influences magnitude of plasticity. spatiotemporal firing patterns produce different effects on the magnitude of synaptic plasticity. Each panel shows the mean subtracted instantaneous firing rate following a trial for a different weight change bin. Neighboring synapses 1–19 (y-axis) shows firing rate (color coded) versus time (x-axis) of 19 nearest neighbors to synapse 0. Synapses with small changes in weight have neighbors that receive average input firing rates. Synapses with intermediate to high weight changes have a few neighbors with higher than average input firing rates.