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. 2022 Sep 29;10(10):2440. doi: 10.3390/biomedicines10102440
CC Cellular component
CD4+ T cells T helper cells also known as CD4-positive cells (CD4 = cluster of differentiation 4)
DEGs differentially expressed genes
E2F group of genes encoding transcription factors in higher eukaryotes
ECP Epithelial Cell Proliferation
FDA U.S. Food and Drug Administration
FTIs farnesyltransferase inhibitors
G2M checkpoint G2/M checkpoint
GEO Gene Expression Omnibus
GO Gene Ontology
GO BPs Gene Ontology enriched biological processes
GSEA Gene Set Enrichment Analysis
HGPS Hutchinson-Gilford progeria syndrome
hsa-mir- human microRNA
iTRAQ isobaric tag for relative and absolute quantification
KEGG Kyoto Encyclopedia of Genes and Genomes
MF molecular function
miR- microRNA
miRNAs microRNAs
miRs microRNAs
MSigDB Molecular Signatures Database
NES normalized enrichment score
PCA Principal component analysis
PRF Progeria Research Foundation
RNA ribonucleic acid
RNA-Seq RNA sequencing
STRING Search Tool for Retrieval of Interacting Genes/Proteins
UV ultraviolet
UVB type B ultraviolet
Genes
ACE2 Angiotensin-converting enzyme 2
ACKR2 Atypical chemokine receptor 2
ACKR4 Atypical chemokine receptor 4
ACTN4P1 Actinin alpha 4 pseudogene 1
ADAM9 ADAM Metallopeptidase Domain 9
ADAMTS A disintegrin and metalloproteinase with thrombospondin motifs
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif 15
ANLN Anillin, Actin Binding Protein
APBA2 Amyloid Beta Precursor Protein Binding Family A Member 2
ASNS Asparagine Synthetase (Glutamine-Hydrolyzing)
ASPA Aspartoacylase
CCL2 C-C Motif Chemokine Ligand 2
CCL26 C-C Motif Chemokine Ligand 26
CCR10 C-C chemokine receptor type 10
CCR11 Abbreviation for Atypical chemokine receptor 4 (ACKR4)
CDH1 Cadherin 1
CDK1 Cyclin Dependent Kinase 1
CDK4 Cyclin Dependent Kinase 4
CDKN2B Cyclin Dependent Kinase Inhibitor 2B
CFH Complement Factor H
CGAS Cyclic GMP-AMP Synthase
CITED2 Cbp/P300 Interacting Transactivator With Glu/Asp Rich Carboxy-Terminal Domain 2
cKRT18 caspase-cleaved fragment of keratin 18 (KRT18)
CLIP4 CAP-Gly Domain Containing Linker Protein Family Member 4
CPNE1 Copine 1
DLGAP5 DLG Associated Protein 5
DTYMK Deoxythymidylate Kinase
ECM2 Extracellular Matrix Protein 2
EDIL3 EGF Like Repeats And Discoidin Domains 3
EFEMP1 EGF containing fibulin extracellular matrix protein 1
EGR1 Early Growth Response 1
FAM8A1 Family With Sequence Similarity 8 Member A1
FBN2 Fibrillin 2
FBLN5 Fibulin 5
FST Follistatin
GDF5 Growth Differentiation Factor 5
HGF Hepatocyte Growth Factor
HS3ST3A1 Heparan Sulfate-Glucosamine 3-Sulfotransferase 3A1
IGF1 insulin-like growth factor 1
IGFBP1 Insulin Like Growth Factor Binding Protein 1
IGFBP2 Insulin Like Growth Factor Binding Protein 2
IGFBP7 Insulin Like Growth Factor Binding Protein 7
IL11 Interleukin 11
IL13RA2 Interleukin 13 Receptor Subunit Alpha 2
IRF6 Interferon Regulatory Factor 6
KDR Kinase Insert Domain Receptor
KIFC1 Kinesin Family Member C1
KIT KIT Proto-Oncogene, Receptor Tyrosine Kinase
KLHL24 Kelch Like Family Member 24
KRAS Kristen rat sarcoma virus
KRT18 Keratin 18
KRT8 Keratin 8
LEPR Leptin Receptor
LMNA Lamin A/C
LMNB1 Lamin B1
LMNB2 Lamin B2
MAF MAF BZIP Transcription Factor
MCP-1 monocyte chemoattractant protein-1
MKI67 Marker Of Proliferation Ki-67
MMP10 Matrix Metallopeptidase 10
MSR1 Macrophage Scavenger Receptor 1
MYL9 Myosin Light Chain 9
NEIL1 Nei Like DNA Glycosylase 1
NTN4 Netrin 4
NKX3-1 NK3 Homeobox 1
NOD1 Nucleotide Binding Oligomerization Domain Containing 1
PLSCR4 Phospholipid Scramblase 4
POLR2F RNA Polymerase II, I And III Subunit F
POSTN Periostin
PRPS1 Phosphoribosyl Pyrophosphate Synthetase 1
PTPRN Protein Tyrosine Phosphatase Receptor Type N
SECTM1 Secreted and Transmembrane 1
SEMA3D Semaphorin 3D
SEMA5B Semaphorin 5B
SIX1 SIX Homeobox 1/Sine Oculis Homeobox Homolog 1
SNAI1 Snail Family Transcriptional Repressor 1
SNAP23 Synaptosome Associated Protein 23
SPINT2 Serine Peptidase Inhibitor, Kunitz Type 2
SPTB Spectrin Beta, Erythrocytic
STAT1 Signal Transducer And Activator Of Transcription 1
STAT4 Signal Transducer And Activator Of Transcription 4
STRA6 Signaling Receptor And Transporter Of Retinol STRA6
SVEP1 Sushi, Von Willebrand Factor Type A, EGF And Pentraxin Domain Containing 1
TACC3 Transforming Acidic Coiled-Coil Containing Protein 3
TLR3 Toll Like Receptor 3
TLR4 Toll Like Receptor 4
TNXB Tenascin XB
TOR1AIP1 Torsin 1A Interacting Protein 1 (also known as LAP1B)
U2AF1 U2 Small Nuclear RNA Auxiliary Factor 1
UBE2D1 Ubiquitin Conjugating Enzyme E2 D1
UCP2 Uncoupling Protein 2
WISP2 WNT1-Inducible-Signaling Pathway Protein 2also known as CCN5 (Cellular Communication Network Factor 5)
Wnt Wingless/Integrated
WNT10B Wnt Family Member 10B
WNT16 Wnt Family Member 16
WNT5A Wnt Family Member 5A