Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Sep 27;12(10):1385. doi: 10.3390/biom12101385

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

ETosis-mediated galectin-10 release. Live eosinophils secrete granule proteins through piecemeal degranulation and exocytosis. Eosinophils have at least two distinct active cell death pathways of apoptosis and ETosis. Unlike apoptotic cells, which are engulfed and digested by phagocytes (efferocytosis), eosinophils can undergo ETosis in tissue and release their cellular content, including cytoplasmic galectin-10, entire secretory granules, and damage-associated molecular patterns. Therefore, ETosis is also considered a form of eosinophil secretion.