Table 1.

Galectin-10 as a biomarker in human diseases.

Disease	Sample	Methods	Purpose/Outcome	Reference
Aspirin-induced asthma	Serum	qRT-PCR	Distinguishing AIA from ATA	[91]
Asthma with or without ABPA	Sputum	Western blot	Correlation with the sputum eosinophil count	[83]
Asthma	Sputum	Inhouse ELISA	Correlation with the sputum eosinophil counts	[92]
Severe asthma	Sputum	RNA transcriptome	The most upregulated gene in severe asthma	[82]
Eosinophilic asthma	Serum	Commercial ELISA	Monitoring after mepolizumab treatment	[84]
Eosinophilic esophagitis	Plasma	Inhouse ELISA	Distinguishing EoE	[88]
Eosinophilic esophagitis	Luminal secretions (esophageal string test)	Inhouse ELISA	Diagnosis of EoE in children	[93]
Eosinophilic esophagitis	Luminal secretions (esophageal string test)	Inhouse ELISA	Distinguishing active EoE in children and adult	[94]
CRSwNP	Nasal secretions	Commercial ELISA	Predicting the glucocorticoid response	[87]
CRSwNP	Nasal brushing	qRT-PCR	Predictive factor for recurrence	[89]
CRSwNP	Nasal polyps	Western blot, qRT-PCR, IHC	Predictive factor for the phenotype	[95]
CRSwNP	Nasal polyps	Commercial ELISA	Correlation with Asp f 1	[90]
CRSwNP	Nasal secretions	IHC	Correlation with severity	[96]
Nonallergic rhinitis with eosinophilia syndrome	Nasal secretions	ELISA	Correlation with severity and treatment	[97]
Atopic dermatitis	Skin specimens, serum	IHC, commercial ELISA	Diagnosis, correlation with severity	[39]
Eosinophilic granulomatosis with polyangiitis	Serum	Commercial ELISA	Correlation with disease activity	[72]

Abbreviations: ABPA, allergic bronchopulmonary aspergillosis; CRSwNP, chronic rhinosinusitis with nasal polyps; qRT-PCR, quantitative real-time polymerase chain reaction; ELISA, enzyme-linked immunosorbent assay; IHC, immunohistochemistry; AIA, aspirin-induced asthma; ATA, aspirin-tolerant asthma; EoE, eosinophilic esophagitis.