Fig. 10.

Demographic reconstruction of lineages B.1.499 and N.5. Estimations of the effective number of infections (inferred from the effective population size multiplied by the generation time, Ne × τ) over time from both lineages are superimposed. Mean values are shown as tick lines and HPD95% values (upper and lower), as thin lines. Dashed lines represent the upper HP95% interval for the time to the most recent common ancestor estimated for each lineage (indicated with arrows). Datasets included 87 sequences for lineage B.1.499 and 53 for N.5, with alignments of 29,782 sites.