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. 2022 Oct 21;12(10):1541. doi: 10.3390/biom12101541

Figure 6.

Figure 6

Type I IFN receptor subunit 1 deficiency is protective against mural angiogenesis in experimental AAAs. Aortic frozen sections from elastase-infused wild type (WT, n = 7) and type I IFN receptor subunit 1-deficient (IFNAR1−/−, n = 12) mice were stained with an anti-mouse CD31 monoclonal antibody to identify neovessels. (A) Representative CD31 immunohistochemical images for neoangiogenesis in AAAs from WT and IFNAR1−/− mice. (B) Mean and standard deviation of mural neoangiogenesis quantified as the number of CD31-positive vessels per aortic cross-section (ACS). Student t’s test, ** p < 0.01 compared to WT mice. Scale bar: 200 μm.