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Mitophagy Modulators Against Mitochondrial Dysfunction. Several factors contribute to the aging process via the mitochondria, including mitophagy, mitochondrial fusion and fission, biogenesis, age-related diseases (i.e., AD and PD), mitochondrial dysfunction in general, and metabolic shifts. STACs, NMN, NR, and resveratrol are compounds that act against the aging process, directly targeting mitophagy and preventing the selective degradation of healthy mitochondria.
